MBS 340 - Molecular Cell Biology

5 CR

Exploration of cellular structure, organization, dynamics and signaling of diverse cell types at the molecular level. The course emphasizes the experiments and techniques used throughout the research process. Topics include biological membranes, protein targeting, the endomembrane system, cell signaling, the cytoskeleton and control of the cell cycle.

Prerequisite(s): MBS 330 or equivalent, with C or higher.

Course Outcomes
After completing this course, students should be able to: • Describe the chemical and electrical properties of membranes • Illustrate the processes of membrane budding, fission, fusion, endocytosis and exocytosis. • Compare and contrast different types of receptors, ligands and signal transduction mechanisms. • Explain the experimental methods used in imaging the cell structure. • Describe the dynamic structure and function of microtubule motors, the microtubule and actin cytoskeletons. • Analyze the mechanics of mitotic chromosome segregation • Explain the principles of cell cycle control including cyclin and CDK signaling, cell cycle checkpoints and DNA damage signaling.

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