MBS 330 - Modern Genetics

5 CR

This course examines the principles of inheritance, the molecular nature of the gene and regulation of gene expression in various systems, and the basis for mutation, variation and evolution. The course begins with an introduction to Mendel’s experiments and culminates in a survey of modern methods in genetics research.

Prerequisite(s): BIOL 160 or BIOL 211 with C or higher.

Course Outcomes
Upon completing this course, students should be able to: • Discuss the principles of classical Mendelian genetics and describe extensions to Mendelian inheritance including gene interactions, epistasis, multiple allelism, and sex-linked transmission. • Describe the role of recombination in generating genetic diversity and explain how recombination frequency is used in mapping chromosomes. • Explain the molecular basis of mutation, and discuss the various types of mutations and their consequences on gene function and health. • Discuss the methods and techniques used in modern genetic research including mutagenesis and genetic screens, genome sequencing, and genetic engineering and evaluate the ethical and moral implications of their application. • Describe the genetic regulation of various developmental processes. • Explain the statistical methods used to analyze quantitative traits and explain experimental approaches used to determine heritability of a trait. • Discuss the application of genetic analysis on the population level.

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