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Sep 17, 2024
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MBS 350 - Bioinformatics 5 CR
Topics include protein and DNA sequence alignments, evolutionary analysis and phylogenetic trees, obtaining protein secondary structure from sequence, and analysis of gene expression including clustering methods.
Prerequisite(s): MBS 340 or equivalent, with a C or higher.
Course Outcomes At the end of this course students will be able to: • Access sequence data on appropriate databases for DNA, RNA and proteins. • Explain and perform pairwise and multiple alignment methods. • Understand and use BLAST (Basic Local Alignment Search Tool) proficiently, together with some more advanced related programs. • Apply different computational strategies used to predict the 3D structure of new proteins. • Explain the experimental techniques used in expressional and functional proteomics and the role of bioinformatics in analyzing the data. • Perform motif and domain searches in protein databases. • Explain microarray technology and microarray data analysis.
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