CHEM 405 - Biochemistry I

5 CR

The first in a two-quarter sequence for students in the Bachelor in Applied Science in Molecular Biosciences, science majors and students interested in careers in pharmacy, dentistry, medicine, veterinary medicine and medical technology. Topics include protein structure and function; carbohydrates and their metabolism, electron transport processes and some of the major metabolic pathways.

Prerequisite(s): BIOL 211 and CHEM 261 or equivalent.

Course Outcomes
After completing this class, students should be able to: • Analyze the structure and physico-chemical properties of amino acids. • Describe in detail all four levels of protein structure. • Discuss the relationship between structure and function (or malfunction) in proteins providing a wide variety of examples. • Illustrate the principles involved in enzymatic catalysis, inhibition and kinetics from both an energetic and a structural standpoint, and apply those principles to a variety of problems. • Delineate the structure, chemical properties and function of relevant carbohydrates. • Describe metabolism in terms of nutrition, high-energy compounds, and thermodynamics concepts. • Delineate glycolysis, glycogen metabolism, the citric acid cycle and the electron transport chain in full stepwise detail including the reactions, the corresponding enzymes and their regulation. • Discuss organ specialization and regulation at the hormonal level of the different metabolic pathways. • Compare and contrast the sequence of reactions that take place during photosynthesis (for plants and cyanobacteria) with the electron transport chain.

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